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Wakefield, Denis; McCluskey, Peter; Wildner, Gerhild; Thurau, Stephan; Carr, Gregory; Chee, Soon-Phaik; Forrester, John; Dick, Andrew; Hudson, Bernard; Lightman, Susan; Smith, Justine and Tugal-Tutkun, Ilknur (2017): Inflammatory eye disease: Pre-treatment assessment of patients prior to commencing immunosuppressive and biologic therapy: Recommendations from an expert committee. In: Autoimmunity Reviews, Vol. 16, No. 3: pp. 213-222

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Abstract

Aim: To outline recommendations from an expert committee on the assessment and investigation of patients with severe inflammatory eye disease commencing immunosuppressive and/or biologic therapy. Method: The approach to assessment is based on the clinical experience of an expert committee and a review of the literature with regard to corticosteroids, immunosuppressive drug and biologic therapy and other adjunct therapy in the management of patients with severe sight-threatening inflammatory eye disease. Conclusion: We recommend a careful assessment and consultative approach by ophthalmologists or physicians experienced in the use of immunosuppressive agents for all patients commencing immunosuppressive and/or biologic therapy for sight threatening inflammatory eye disease with the aim of preventing infection, cardiovascular, metabolic and bone disease and reducing iatrogenic side effects.

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