Abstract
We demonstrate a flexible stand-alone video-endomicroscope with an outer diameter of less than 2.0 mm that enables surgeons and biologists to image hardly accessible, intracorporeal regions in-vivo in epifluorescence mode. The 60 mg light device improves state-of-the-art objectives by a double deflection approach using a side-fire fiber in combination with spherical microlenses, GRIN-lenses with a specific adapted gradient index profile and an extremely miniaturized chip-on-the-tip camera to achieve an excellent imaging quality. A high NA of 0.7 enables the observation of subcellular features within the entire field of view with a diameter of around 200 mu m, assure a bright and high-contrast image and promise a good overview during the intervention. Ex-vivo measurements of biological samples confirmed the functionality of the probe.
Dokumententyp: | Zeitschriftenartikel |
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Fakultät: | Medizin |
Themengebiete: | 600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin und Gesundheit |
ISSN: | 0277-786X |
Sprache: | Englisch |
Dokumenten ID: | 55455 |
Datum der Veröffentlichung auf Open Access LMU: | 14. Jun. 2018, 09:59 |
Letzte Änderungen: | 04. Nov. 2020, 13:35 |