Maier, Alexander Mario; Bae, Wooli; Schiffels, Daniel; Emmerig, Johannes Friedrich; Schiff, Maximilian; Liedl, Tim (2017): Self-Assembled DNA Tubes Forming Helices of Controlled Diameter and Chirality. In: Acs Nano, Vol. 11, No. 2: pp. 1301-1306 |
Abstract
Multihelical DNA bundles could enhance the functionality of nanomaterials and serve as model architectures to mimic protein filaments on the molecular and cellular level. We report the self-assembly of micrometer-sized helical DNA nanotubes with widely controllable helical diameters ranging from tens of nanometers to a few micrometers. Nanoscale helical shapes of DNA tile tubes (4-, 6-, 8-, 10-, and 12-helix tile tubes) are achieved by introducing discrete amounts of bending and twist through base pair insertions and/or deletions. Microscale helical diameters, which require smaller amounts of twist and bending, are achieved by controlling the intrinsic "supertwist" present in tile tubes with uneven number of helices (11-, 13-, and 15-helix tile tubes). Supertwist fine-tuning also allows us to produce helical nanotubes of defined chirality.
Item Type: | Journal article |
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Faculties: | Physics |
Research Centers: | Center for NanoScience (CENS) |
Subjects: | 500 Science > 530 Physics 500 Science > 500 Science |
ISSN: | 1936-0851 |
Language: | English |
ID Code: | 55724 |
Deposited On: | 14. Jun 2018 10:00 |
Last Modified: | 04. Nov 2020 13:36 |