ORCID: https://orcid.org/0000-0002-8038-4547 and Krotz, Oswald
(2018):
A Concept for a Novel Test for Chemical Parity.
In: Green and Sustainable Chemistry, Vol. 8, No. 4: pp. 311-319
[PDF, 819kB]

Abstract
Deviations from chemical parity (PV) were evaluated with the search for very small enantiomeric excesses in a racemate prepared from non chiral materials and were detected by means of the circular dichroism (CD). Thus, intensely light-absorbing perylenebiscarboximides were attached to axially chiral biphenyls for the amplification of CD effects by exciton interactions of the adjacent chromophores. A rapidly racemising system was applied for the exclusion of artifacts and compared with an analogous with locked chirally. A very slight enantiomeric excess was detected for the (M) enantiomer. Application of the method for other systems was suggested and relations to natural products discussed.
Item Type: | Journal article |
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Form of publication: | Publisher's Version |
Keywords: | Chirality; Parity; Circular Dichroism; UV/Vis Spectroscopy; Racemates |
Faculties: | Chemistry and Pharmacy > Department of Chemistry |
Subjects: | 500 Science > 540 Chemistry |
URN: | urn:nbn:de:bvb:19-epub-58844-3 |
ISSN: | 2160-696X |
Language: | English |
Item ID: | 58844 |
Date Deposited: | 06. Nov 2018, 09:10 |
Last Modified: | 04. Nov 2020, 13:37 |