Flavin-Induced DNA Photooxidation and Charge Movement Probed by Ultrafast Transient Absorption Spectroscopy

Wenninger, Matthias; Fazio, Danila; Megerle, Uwe; Trindler, Christian; Schiesser, Stefan; Riedle, Eberhard und Carell, Thomas (März 2011): Flavin-Induced DNA Photooxidation and Charge Movement Probed by Ultrafast Transient Absorption Spectroscopy. In: ChemBioChem, Bd. 12, Nr. 5: S. 703-706

Abstract

Quantum yields of up to 14 % for the formation of a long‐lived, charge‐separated state can be achieved in flavin‐capped DNA hairpins. The excited flavin state is quenched by electron‐transfer processes from adjacent DNA bases. The introduction of multiple (dG:dC) base pairs leads to efficient hole trapping that competes with the charge recombination through dA‐hopping processes.

• Dokumententyp: Zeitschriftenartikel
• Fakultät: Physik
• Themengebiete: 500 Naturwissenschaften und Mathematik > 530 Physik
• ISSN: 1439-4227
• Sprache: Englisch