Abstract
Background: The purpose of this study was to evaluate the stress distribution patterns within the viscero-and neurocranium of neonates during nasoalveolar molding. Methods: Finite element models of 3 different healthy neonates at different times of life (date of birth, 4 weeks, and 3.5 months) were generated on the basis of computed tomography scans. A validated workflow, including segmentation, meshing, setting of boundary conditions, and implementation of a bone density-dependent material model, was carried out for each model. A small and a large unilateral alveolar and hard palatal cleft were virtually cut in each model. The stress distribution pattern in each model was then analyzed by using Ansys APDL. Results: Convergence analysis validated the results. The virtual experiments at the date of birth showed a stress pattern above a previously defined threshold value of 30,000 Pa in the ipsilateral naso-orbital-complex, frontal sinus, and the anterior fossa of the base of the skull, with von Mises values > 35,000 Pa. Stress patterns at the age of 4 weeks and 3.5 months showed reduced von Mises values at < 15,000 Pa. Conclusions: Nasoalveolar molding therapy is a safe presurgical treatment modality without significant influence on the viscero-and neurocranium of neonates. Treatment, considering the stress distribution at the naso-orbital-complex and anterior fossa of the base of the skull, should begin in the second week of life, and treatment initiation of preterm infants should be adapted respectively.
Dokumententyp: | Zeitschriftenartikel |
---|---|
Fakultät: | Medizin |
Themengebiete: | 600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin und Gesundheit |
URN: | urn:nbn:de:bvb:19-epub-63421-3 |
ISSN: | 2169-7574 |
Sprache: | Englisch |
Dokumenten ID: | 63421 |
Datum der Veröffentlichung auf Open Access LMU: | 19. Jul. 2019, 12:13 |
Letzte Änderungen: | 04. Nov. 2020, 13:41 |