Extracellular Vesicles as Biomarkers in Cardiovascular Disease;Chances and Risks

Dickhout, Annemiek and Könen, Rory R. (2018): Extracellular Vesicles as Biomarkers in Cardiovascular Disease;Chances and Risks. In: Frontiers in Cardiovascular Medicine, Vol. 5, 113

Abstract

The field of extracellular vesicles (EV) is rapidly expanding, also within cardiovascular diseases. Besides their exciting roles in cell-to-cell communication, EV have the potential to serve as excellent biomarkers, since their counts, content, and origin might provide useful information about the pathophysiology of cardiovascular disorders. Various studies have already indicated associations of EV counts and content with cardiovascular diseases. However, EV research is complicated by several factors, most notably the small size of EV. In this review, the advantages and drawbacks of EV-related methods and applications as biomarkers are highlighted.

• Item Type: Journal article
• Faculties: Medicine
• Subjects: 600 Technology > 610 Medicine and health
• ISSN: 2297-055X
• Language: English