ORCID: https://orcid.org/0000-0002-9817-9875 and Bartenstein, Peter
(2018):
Advanced neuroendocrine tumours of the small intestine and pancreas: clinical developments, controversies, and future strategies.
In: Lancet Diabetes & Endocrinology, Vol. 6, No. 5: pp. 404-415
Abstract
In this Review, we discuss clinical developments and controversies in the treatment of neuroendocrine tumours (NETs) that are relevant for clinicians and clinical researchers. We describe advances in genetics, blood-based biomarkers, functional imaging, and systemic therapy of advanced NETs and discuss results of recent phase 3 studies, systemic treatment of advanced disease with peptide receptor radionuclide therapy, biotherapy, chemotherapy, and molecularly targeted therapy, and the potential role of immunotherapy in the treatment of NETs. Suggested treatment algorithms for NETs of ileal or jejunal origin and of pancreatic origin are presented.
| Item Type: | Journal article |
|---|---|
| Faculties: | Medicine |
| Subjects: | 600 Technology > 610 Medicine and health |
| ISSN: | 2213-8587 |
| Language: | English |
| Item ID: | 63778 |
| Date Deposited: | 19. Jul 2019, 12:14 |
| Last Modified: | 04. Nov 2020, 13:42 |
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