Cervical dysplasia during pregnancy - Effects on oncological and psychological outcome: a case control study

Rueckert, S.; Oestreich, K.; Gallwas, J.; Kolben, T.; Ditsch, N.; Starrach, T.; Blume, C.; Dannecker, C. and Kolben, T. M. (2018): Cervical dysplasia during pregnancy - Effects on oncological and psychological outcome: a case control study. In: European Journal of Gynaecological Oncology, Vol. 39, No. 3: pp. 399-403

Abstract

Pregnant patients with cervical intraepithelial neoplasia Grade 3 (CIN 3) are monitored in 8- to 12-weekly intervals unless invasive carcinoma is suspected. The aim of this case-control study was to evaluate differences in regression and healing rates as well as post-traumatic stress levels. Materials and Methods: Treatment and outcome were analysed retrospectively. Stress levels were measured using the standardized German version of the Impact of Event Scale-Revised (IES-R) questionnaire. Results: Spontaneous regression was seen in 26.9% of cases. Progression to invasive cancer was not detected. 88.2% of all pregnant and 88.3% of all non-pregnant women were regarded as healed. Stress level was not significantly higher in non-pregnant patients. Conclusion: Cervical dysplasia in pregnancy shows high spontaneous regression potential. Regression is associated with long-time healing of dysplasia. An observant approach in patients with CIN3 during pregnancy does not cause higher stress levels.

• Item Type: Journal article
• Faculties: Medicine
• Subjects: 600 Technology > 610 Medicine and health
• ISSN: 0392-2936
• Language: English