The importance of hCG in human endometrial adenocarcinoma and breast cancer

Koelbl, Alexandra C.; Schlenk, Kristina; Behrendt, Nils und Andergassen, Ulrich (2018): The importance of hCG in human endometrial adenocarcinoma and breast cancer. In: International Journal of Biological Markers, Bd. 33, Nr. 1: S. 33-39

Abstract

Human chorionic gonadotropin (hCG) is a peptide hormone which plays an important role during pregnancy. But its impact is not limited to pregnancy;it also influences tumor formation and metastatic outgrowth, especially in endometrial adenocarcinoma and breast cancer. This review summarizes what has been written in the literature about the role of hCG as a tumor marker in these 2 gynecological malignancies and also about the signal transduction pathways in which hCG is involved. HCG can, on the one hand, be a marker for the progression of a malignant disease, and on the other hand, it may be a point for therapeutical intervention, so further research into this molecule would be very much worthwhile.

• Dokumententyp: Zeitschriftenartikel
• Fakultät: Medizin
• Themengebiete: 600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin und Gesundheit
• ISSN: 0393-6155
• Sprache: Englisch