Abstract
Objective: This single center study compared the risk of bacterial endocarditis (BE) after surgical and percutaneous pulmonary valve implantation. Methods: Between Jan 1st 2010 and Dec 31st 2015 all patients who received a biological pulmonary valve (surgical/interventional) were identified. The clinical follow-up was analyzed with regard to BE applying the modified Duke criteria and echocardiographic findings. Results: We identified 246 patientswho underwent a biological pulmonary valve implantation. Themean agewas 15.9 years, (SD 12.7, Median 13.1). There were 166 surgical patients (67.5%), with 55 homografts (22.4%, mean diameter 27.4mm), 106 Contegra (R) grafts (43.1%, mean diameter 17.4) and 5 Hancock (R) valves (2.0, mean diameter 25.6 mm) and 80 percutaneous pulmonary valve implantations (PPVI) (32.5%) with 51 Edwards Sapien (R) valves (20.7%, mean diameter 25.2 mm) and 29 Melody (R) valves (11.8%, mean diameter 21.9 mm). Patients with a bovione jugular conduit as the biologiocal substrate had an increased risk for BE and patientswithMelody (R) valves had the highest risk for BE that was 5-8 times higher as compared to other valves. BE episodes were detected in 5/106 Contegras (R) (4,7%, 1.5 per 100 person-years), and in 6/29 of the Melody (R) valves (20.7%, 4.8 per 100 person-years). There were no cases of BE in patients treated with Edwards Sapien (R), homografts or Hankock (R) valves. Conclusion: Whereas homografts and Edwards Sapien (R) valves seem to have a very low risk of BE, this risk is increased in Contegra (R) conduits and in Melody (R) valves.
| Item Type: | Journal article |
|---|---|
| Faculties: | Medicine |
| Subjects: | 600 Technology > 610 Medicine and health |
| ISSN: | 0167-5273 |
| Language: | English |
| Item ID: | 64271 |
| Date Deposited: | 19. Jul 2019, 12:14 |
| Last Modified: | 04. Nov 2020, 13:43 |
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