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Burgard, Caroline A.; Dinkel, Julien; Strobl, Frederik; Paprottka, Philipp M.; Schramm, Nicolai; Reiser, Maximilian und Trumm, Christoph G. (2018): CT fluoroscopy-guided percutaneous osteoplasty with or without radiofrequency ablation in the treatment of painful extraspinal and spinal bone metastases: technical outcome and complications in 29 patients. In: Diagnostic and Interventional Radiology, Bd. 24, Nr. 3: S. 158-165

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Abstract

PURPOSE We aimed to assess the safety and technical outcome of computed tomography (CT) fluoroscopy-guided osteoplasty with or without prior percutaneous radiofrequency ablation (RFA) in patients with painful osteolyses. METHODS We performed a retrospective analysis of 29 patients with painful extraspinal and spinal osteolyses (16 women, 13 men;63.1 +/- 14.4 years) who under went CT fluoroscopy-guided osteoplasty (10-20 mAs tube current) with or without RFA (26 arid 14 lesions, respectively), in 33 consecutive procedures from 2002 to 2016. Technical success was defined as at least one complete RFA cycle arid subsequent polymethyl metacrylate (PMMA) bone cement injection covering >= 75% of longest diameter of extraspinal osteolysis on axial plane or of distance between vertebral endplates. Procedure-related complications within 30 days and dose-length-product (DLP) were also evaluated. RESULTS Osteolyses were located in the pelvis (acetabulum, n=10;iliac bone, n=4), spine (thoracic, n=6;lumbar, n=5;sacral, n=8), long bones (femur, n=3;tibia, n=1), sternum (n=2) and glenoid (n=1). Mean size of the treated osteolysis was 4.0 +/- 1.2 cm (range, 1.9-6.9 cm). Of 40 osteolyses, 31 (77.5%) abutted neighboring risk structures (spinal canal or neuroforamen, n=18;neighboring joint, n=11;other, n=8). Mean number of RFA electrode positions and complete ablation cycles was 1.5 +/- 0.9 and 2.1 +/- 1.7, respectively. Mean PMMA filling volume was 7.7 +/- 5.7 mL (range, 2-30 mL). Small asymptomatic PMMA leakages were observed in 15 lesions (37.5%). Mean total DLP was 850 +/- 653 mGy*cm. Six minor complications were observed, without any major complications. CONCLUSION CT Fluoroscopy-guided percutaneous osteoplasty with or without concomitant RFA for the treatment of painful extraspinal and spinal osteolyses can be performed with a low complication rate and high technical success.

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