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Brado, Johannes; Odening, Katja E. (2018): Familiäre Arrhythmieerkrankungen mit strukturell normalen Herzen. In: Aktuelle Kardiologie, Vol. 7, No. 3: pp. 190-196
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Inherited cardiac channelopathies are frequent causes of arrhythmogenic syncope and sudden cardiac death in young adults. When timely diagnosed and treated properly, they can be well controlled with anti-arrhythmic therapy and ICDs. Adequate risk stratification is crucial in the management of these diseases. As the individual arrhythmogenic risk can change over time, regular follow-ups are indicated. An increasing understanding of the genetic and pathophysiologic mechanisms of these diseases leads to the development of more targeted (mechanism-based) therapies.