Interventioneller PFO-Verschluss. Konsensuspapier der Arbeitsgruppe Interventionelle Kardiologie (AGIK) der Deutschen Gesellschaft für Kardiologie – Herz- und Kreislaufforschung (DGK) gemeinsam mit der Deutschen Gesellschaft für Neurologie (DGN) und der Deutschen Schlaganfallgesellschaft (DSG)

Ghanem, A.; Liebetrau, C.; Diener, H. -C.; Elsaesser, A.; Grau, A.; Groeschel, K.; Mattle, H.; Massberg, S.; Möllmann, H.; Nef, H.; Sander, D.; Weimar, C.; Woehrle, J. und Baldus, S. (2018): Interventioneller PFO-Verschluss. Konsensuspapier der Arbeitsgruppe Interventionelle Kardiologie (AGIK) der Deutschen Gesellschaft für Kardiologie – Herz- und Kreislaufforschung (DGK) gemeinsam mit der Deutschen Gesellschaft für Neurologie (DGN) und der Deutschen Schlaganfallgesellschaft (DSG). In: Kardiologe, Bd. 12, Nr. 6: S. 415-423

Abstract

Almost every second patient with cryptogenic stroke has apatent foramen ovale (PFO). This consensus document firstly provides an evidence-based overview on the diagnostics of PFO, current studies, interventional closure, and medical therapy in terms of platelet aggregation inhibitors and anticoagulation. Secondly, the risk-benefit balance of interventional versus antithrombotic therapy with and without oral anticoagulants in patients with cryptogenic stroke and PFO is discussed based on recent findings of randomized controlled clinical trials (RCTs) and meta-analyses. Ultimately, the consented recommendations and levels thereof are indicated. The published data demonstrate the superiority of interventional PFO closure. There is asignificant reduction of recurrent strokes in patients with an interventional PFO closure device compared to medical therapy. The complication rate of the interventional therapy is low and particularly younger patients with cryptogenic stroke benefit from interventional PFO closure. In summary, interventional PFO closure is superior to medical treatment in patients with cryptogenic stroke aged <60years.

• Dokumententyp: Zeitschriftenartikel
• Fakultät: Medizin
• Themengebiete: 600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin und Gesundheit
• ISSN: 1864-9718
• Sprache: Deutsch