Liu, Xing; Zhang, Shi-Bo; Zhu, Hui; Cheng, Yu; Peng, Han-Ying; Dong, Zhi-Bing (2018): An Efficient Chan-Lam S-Arylation of Arylthioureas with Arylboronic Acids. In: European Journal of Organic Chemistry, No. 32: pp. 4483-4489 |
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Abstract
A convenient and efficient protocol has been developed for the preparation of aryl-isothioureas based on the Chan-Lam C-S coupling reaction. The desired aryl-isothioureas were synthesized in good yields (up to 95%) in the presence of Cu(OAc)(2)H2O as catalyst and bipyridine as ligand. A variety of functional groups on the aryl-thiourea and arylboronic acid reagents are tolerated. The method features mild reaction conditions and good yields, thereby illustrating its practical synthetic value in organic synthesis.
Item Type: | Journal article |
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Faculties: | Chemistry and Pharmacy > Department of Chemistry |
Subjects: | 500 Science > 540 Chemistry |
ISSN: | 1434-193X |
Language: | English |
ID Code: | 67354 |
Deposited On: | 19. Jul 2019 12:22 |
Last Modified: | 04. Nov 2020 13:49 |
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