Supramolecular chirality transfer in a stereodynamic catalysts

Storch, Golo und Trapp, Oliver (2018): Supramolecular chirality transfer in a stereodynamic catalysts. In: Chirality, Bd. 30, Nr. 10: S. 1150-1160

Abstract

We present rhodium catalysts that contain stereodynamic axially chiral biphenol-derived phosphinite ligands modified with non-stereoselective amides for non-covalent interactions. A chirality transfer was achieved with (R)- or (S)-acetylphenylalanine methyl amide, and the interaction mechanism was investigated by NMR measurements. These interactions at the non-stereoselective interaction sites and the formation of supramolecular complexes result in an enrichment of either the (R-ax)- or (S-ax) enantiomer of the tropos catalysts, which in turn provide the (R)- or (S)-acetylphenylalanine methyl ester in the hydrogenation of (Z)-methyl--acetamidocinnamate.

• Dokumententyp: Zeitschriftenartikel
• Fakultät: Chemie und Pharmazie > Department Chemie
• Themengebiete: 500 Naturwissenschaften und Mathematik > 540 Chemie
• ISSN: 0899-0042
• Sprache: Englisch