Parallel Approaches for the Functionalization of Thietes: alpha-Metalation versus C-H Activation

Eisold, Michael; Miiller-Deku, Adrian; Reiners, Felix and Didier, Dorian (2018): Parallel Approaches for the Functionalization of Thietes: alpha-Metalation versus C-H Activation. In: Organic Letters, Vol. 20, No. 15: pp. 4654-4658

Abstract

For the first time, an approach to 3,4disubstituted thietes was developed through two complementary paths. While the first one relies on alpha-metalation, the second is based on direct C-H functionalization. A new library of sophisticated sulfur-containing four-membered rings is described, paving the way to new bioactive analogues and small heterocycle incorporation.

• Item Type: Journal article
• Faculties: Chemistry and Pharmacy > Department of Chemistry
• Subjects: 500 Science > 540 Chemistry
• ISSN: 1523-7060
• Language: English