Impaired biotin status in anticonvulsant therapy

Krause, Klaus-Henning; Berlit, Peter und Bonjour, Jean-Pierre (1982): Impaired biotin status in anticonvulsant therapy. In: Annals of Neurology, Bd. 12, Nr. 5: S. 485-486

Abstract

In 264 epileptics undergoing long-term therapy with anticonvulsants, significantly reduced plasma biotin levels were found compared with a normal control group: 74% of the epileptics had biotin levels for those treated with sodium valproate were higher than for those treated with phenytion, primidone, or carbamazepine. The observed reduction in biotin levels might be a factor influencing the efficacy of these three antionvulsants.

• Dokumententyp: Zeitschriftenartikel
• Fakultät: Medizin
• Themengebiete: 600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin und Gesundheit