Logo Logo
Help
Contact
Switch Language to German

Krause, Klaus-Henning; Berlit, Peter and Bonjour, Jean-Pierre (1982): Impaired biotin status in anticonvulsant therapy. In: Annals of Neurology, Vol. 12, No. 5: pp. 485-486 [PDF, 220kB]

Abstract

In 264 epileptics undergoing long-term therapy with anticonvulsants, significantly reduced plasma biotin levels were found compared with a normal control group: 74% of the epileptics had biotin levels for those treated with sodium valproate were higher than for those treated with phenytion, primidone, or carbamazepine. The observed reduction in biotin levels might be a factor influencing the efficacy of these three antionvulsants.

Actions (login required)

View Item View Item