Plasma arginine vasopressin concentrations in epileptics under monotherapy

Krause, Klaus-Henning; Rascher, W. and Berlit, Peter (1983): Plasma arginine vasopressin concentrations in epileptics under monotherapy. In: Journal of Neurology, Vol. 230, No. 3: pp. 193-196

Abstract

Plasma arginine vasopressin concentrations were determined by radio-immunoassay in 112 adult epileptics who were taking carbamazepine, phenytoin, primidone, or sodium valproate in long-term monotherapy, and in 19 controls. No significant difference was found between the groups, but some epileptics taking carbamazepine and primidone showed low values. Serum concentrations of carbamazepine did not correlate with the concentrations of plasma arginine vasopressin.

In conclusion, there was no evidence of a stimulating effect of chronic carbamazepine medication or a special inhibiting effect of phenytoin on the release of vasopressin arginine from the posterior pituitary.

• Item Type: Journal article
• Keywords: Arginine vasopressin, Carbamazepine, Anticonvulsants, Epilepsy
• Faculties: Medicine
• Subjects: 600 Technology > 610 Medicine and health
• ISSN: 1432-1459