Abstract
Uric acid examination in 554 epileptic out-patients under long-term anticonvulsant medication revealed significantly lower serum concentrations compared to a group of normal controls. In patients taking enzyme-inducing drugs, uric acid levels were found to be lower than in those under valproate sodium. In addition, uric acid concentrations showed a negative correlation with duration of therapy in epileptic males. At this time, we can only speculate on the mechanism involved in the reduction of uric acid by enzyme-inducing anticonvulsants as well as on the possible implication of this finding in the treatment of hyperuricemia.
| Item Type: | Journal article |
|---|---|
| Keywords: | Uric acid, Anticonvulsants, Enzyme induction |
| Faculties: | Medicine |
| Subjects: | 600 Technology > 610 Medicine and health |
| URN: | urn:nbn:de:bvb:19-epub-7413-0 |
| Item ID: | 7413 |
| Date Deposited: | 12. Nov 2008 14:41 |
| Last Modified: | 04. Nov 2020 12:50 |
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