Mitochondrial import receptors for precursor proteins

Pfanner, Nikolaus; Söllner, Thomas und Neupert, Walter (1991): Mitochondrial import receptors for precursor proteins. In: Trends in Biochemical Sciences, Bd. 16: S. 63-67

Abstract

The specific targeting of precursor proteins synthesized in the cytosol to various cell organelles is a central aspect of intracellular protein traffic. Several hundred different proteins are imported from the cytosol into the mitochondria. Recent studies have identified the mitochondrial outer membrane proteins MOM19, MOM72, MOM38 (≈ISP42) and p32 which have a role in initial steps of protein import. The first three components are present in a multi-subunit complex that catalyses recognition and membrane insertion of precursor proteins.

• Dokumententyp: Zeitschriftenartikel
• Fakultät: Medizin
• Themengebiete: 600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin und Gesundheit
• ISSN: 0968-0004