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Stana, Jan ORCID logoORCID: https://orcid.org/0000-0002-0013-7870; Fernandez Prendes, Carlota ORCID logoORCID: https://orcid.org/0000-0002-6445-0575; Kruszyna, Lukasz ORCID logoORCID: https://orcid.org/0000-0001-5205-5765; Ruffino, Maria Antonella; Passaloglou, Ioannis Thomas; Reyes Valdivia, Andrés ORCID logoORCID: https://orcid.org/0000-0001-6282-1099; Castro Madrazo, Jose Antonio del; Oikonomou, Kyriakos; Chan, Hon Lai; Makaloski, Vladimir ORCID logoORCID: https://orcid.org/0000-0001-8826-3232 und Tsilimparis, Nikolaos (2021): Multicenter Experience With Large Diameter Balloon-Expandable Stent-Grafts for the Treatment of Infrarenal Penetrating Aortic Ulcers. In: Journal of Endovascular Therapy, Bd. 28, Nr. 6: S. 871-877 [PDF, 536kB]

Abstract

Purpose: To describe the use of large-diameter balloon-expandable stent-grafts (BeGraft aortic stent-graft, Bentley InnoMed GmbH, Hechingen, Germany) in the treatment of infrarenal penetrating aortic ulcer (iPAU).

Materials and Methods: Retrospective analysis of patients undergoing endovascular treatment with the BeGraft aortic stent-graft in 8 European centers from January 2017 to October 2020. Demographics, perioperative data, and midterm outcomes were collected. Endpoints of the study were technical feasibility, early mortality, and morbidity.

Results: A total of 40 patients were included. The mean age was 73.9±7.05 years and 63.2% were male. Indications for treatment included size and morphology (65%), presence of symptoms (29.5%), and contained ruptures (5.5%). Urgent treatment was performed in 5% of cases. Technical success was 97.5%. Median operation time was 58 minutes (19–170 minutes), with 27.5% of patients having additional procedures during the main intervention (1 additional repair with a C-TAG (W.L. Gore & Associates, Inc, Flagstaff, AZ, USA) thoracic endoprosthesis, 5 covered endovascular reconstruction of aortic bifurcation procedures, 3 extensions with proximal cuffs, and 2 percutaneous angioplasties of the common iliac arteries). Percutaneous femoral access was used in 72.5%, while groin cut-down was performed in 27.5%. Repair was successful with only 1 stent in 45% of cases, while 37.5% required 2 stents and nearly 17.5% required 3/4 stent-grafts. The 30-day mortality was 0%, with a 2.5% reintervention rate (1 patient required evacuation of an intra-abdominal hematoma). Median follow-up was 13.9 months (2–39 months), during which no vascular-related reinterventions or deaths were reported. In 4 patients, a type II endoleak was observed. No cases of graft migration, thrombosis, or stent-fracture were observed.

Conclusions: The treatment of iPAU with the BeGraft aortic stent-graft in a selective patient group is feasible with low rate of perioperative morbidity and mortality. Balloon-expandable stent-grafts offer the option to repair iPAUs with a shorter coverage of the aorta using low-profile sheath, that enables treatment in the presence of calcified access vessels and small diameter aortic bifurcations.

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