Molekulare Klassifikatoren. Reif für die Klinik?

Weigert, Oliver und Chapuy, Björn (2019): Molekulare Klassifikatoren. Reif für die Klinik? In: Onkologe, Bd. 25, Nr. 10: S. 849-858

Abstract

Background. Non-Hodgkin lymphomas are clinically and molecularly heterogeneous diseases. In addition to clinical symptoms, morphology and immunophenotype, molecular diagnostics are increasingly used to more accurately classify lymphomas into homogeneous, clinically relevant and non-overlapping entities. Conclusion. Molecular classifiers are used to improve the diagnostic accuracy of entities, to detect the biological heterogeneity in an entity in more detail and to develop prognostic and/or predictive biomarkers. This article reviews the recent developments in molecular classifiers focusing on follicular lymphoma and diffuse large B-cell lymphoma.

• Dokumententyp: Zeitschriftenartikel
• Fakultät: Medizin
• Themengebiete: 600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin und Gesundheit
• ISSN: 0947-8965
• Sprache: Deutsch