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Soyka, Michael; Pogarell, Oliver (2019): Neue Slow-release-Buprenorphinformulierungen zur Optimierung der Opioidsubstitution. In: Nervenarzt, Vol. 90, No. 9: pp. 932-937
Full text not available from 'Open Access LMU'.

Abstract

Opioid maintenance treatment with methadone or buprenorphine is an established first-line treatment for opioid dependence. In addition to the novel weekly and monthly subcutaneously injectable buprenorphine depot CAM 2038 (Buvidal (R)), which is already available in Germany, two other long-acting buprenorphine formulations may be introduced in the near future: the monthly depot formulation RBP-6000 (Sublocade (TM)) and a 6-month buprenorphine depot implant (Probuphine (TM)). Basic pharmacological and clinical data of these three medications are given and possible clinical applications are discussed.