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Westphalen, C. Benedikt; Heinrich, Kathrin; Böck, Stefan und Heinemann, Volker (2019): Molekulare Charakterisierung des Pankreaskarzinoms. Therapeutische Implikationen. In: Onkologe, Bd. 25, Nr. 8: S. 704-709

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Abstract

BackgroundPrecision oncology has achieved significant successes in the treatment of many malignant diseases. Based on comprehensive molecular profiling the treatment reality of many tumors has been decisively changed and in part been revolutionized. Along the same lines, there is agrowing body of knowledge with respect to the molecular pathology of pancreatic cancer. The aim of this article is to briefly outline potential therapeutic strategies to implement precision oncology in the treatment of pancreatic cancer.ConclusionWhile there is growing knowledge about the molecular pathology of pancreatic cancer, this knowledge has not been translated into achange in management or an improvement of the dismal prognosis of pancreatic cancer. Nevertheless, even today some patients with pancreatic cancer might profit from extended molecular diagnostics.

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