Asthma im Kindes- und Erwachsenenalter

Maison, Nicole (2019): Asthma im Kindes- und Erwachsenenalter. In: Pneumologe, Bd. 16, Nr. 2: S. 98-103

Abstract

BackgroundDue to its heterogeneous appearance bronchial asthma is nowadays considered to be more acomplex syndrome than asingle disease. Onset in infancy, childhood, school age, adolescence and adulthood, diseases with persistent or recurrent obstructive symptoms triggered by infections, allergens and physical activity, with mild and severe courses are summarized.AimIdentification of phenotypes and endotypes which are associated with persistence from childhood into adulthood.MethodsA review of the literature was carried out and a summary is presented.ResultsWheeze due to obstructive airway complaints in infancy is known to be apredictor for asthma in adulthood. Many infants, particularly male individuals without allergic comorbidities, lose their symptoms up to the age of 6 years, in contrast others do so during puberty. Symptoms can emerge or recur during adolescence or adulthood. Infants with early onset and distinct symptoms are at high risk to develop apersistent and progressive course with severe health restrictions in adulthood. Other risk factors are atopy, allergies, severe pulmonary infections, genetic disposition, positive family history and environmental conditions, such as active and passive smoking.ConclusionIndividuals at risk for severe persistent bronchial asthma deserve closer clinical attention and research to develop adequate treatment approaches and prevention strategies. The transition of this heterogeneous disease from infancy to adulthood must therefore be accompanied clinically and in research.

• Dokumententyp: Zeitschriftenartikel
• Fakultät: Medizin
• Themengebiete: 600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin und Gesundheit
• ISSN: 1613-5636
• Sprache: Deutsch