Abstract
Objectives: To characterize video head impulse testing (vHIT) in definitive Meniere's disease and to investigate the relationship between vHIT results and other audiovestibular function tests. Design: Fifty-four patients with certain Meniere's disease, that is, patients with clinically definite Meniere's disease and endolymphatic hydrops visualized by locally enhanced inner ear MR imaging, were recruited for this study. All patients underwent vHIT. The vestibular-ocular reflex gain at 60ms and refixation saccades were the outcome parameters measured. Saccades were characterized by determining the saccade frequency, their mean latency, and their mean velocity. Results: Seven of 54 patients had bilateral normal vHITs. Clearly pathologically vHITs with decreased gain and refixation saccades were observed in further seven patients. The majority of patients exhibited vHITs with refixation saccades but normal gain. Saccades mostly occurred bilaterally. There was no correlation between vHIT gain or saccades and caloric irrigation, cervical vestibular evoked myogenic potential or audiometry for Meniere's ears. Furthermore, vHIT gain or saccades correlated neither with age nor with the duration of the disease. Conclusions: Pathological low vHIT gain values are rarely observed in patients with certain Meniere's disease, while refixation saccades occur very frequently. In the majority of patients, saccades occur bilaterally. In Meniere's disease, in contrast to vestibular neuritis, there is no compensatory decrease of saccade latency over time.
Item Type: | Journal article |
---|---|
Faculties: | Medicine |
Subjects: | 600 Technology > 610 Medicine and health |
ISSN: | 0196-0202 |
Language: | English |
Item ID: | 80842 |
Date Deposited: | 15. Dec 2021, 14:55 |
Last Modified: | 15. Dec 2021, 14:55 |