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Schulte-Baukloh, Heinrich; Bauer, Ricarda; Jost, Wolfgang; Wissel, Jörg; van Ophoven, Arndt (2019): Botulinumtoxin bei Blasenfunktionsstörungen. In: Fortschritte der Neurologie Psychiatrie, Vol. 87, No. 1: pp. 23-30
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Abstract

An overactive neurogenic detrusor and an non-neurogenic overactive bladder both exhibit symptoms such as urgency and frequency, both with and without urinary incontinence, and are often accompanied by nocturia. OnabotulinumtoxinA-Detrusorinjection has become well established as a second line therapy in cases where anticholinergic medication has failed. The procedure can be performed under general or local anesthesia, in both in- and outpatient settings. The side effects of the procedure are primarily urinary tract infections and - especially in neurogenic bladder patients - urinary retention. This article focuses on the approved indications and summarizes the current scientific data.