Dynamic host-guest interaction enables autonomous single molecule blinking and super-resolution imaging

Sasmal, Ranjan; Das Saha, Nilanjana; Schueder, Florian; Joshi, Divyesh; Sheeba, Vasu; Jungmann, Ralf und Agasti, Sarit S. (2019): Dynamic host-guest interaction enables autonomous single molecule blinking and super-resolution imaging. In: Chemical Communications, Bd. 55, Nr. 96: S. 14430-14433

Abstract

Synthetic host-guest complexes are inherently dynamic as they employ weak and reversible noncovalent interactions for their recognition processes. We strategically exploited dynamic supramolecular recognition between fluorescently labeled guest molecules to complementary cucurbit[7]uril hosts to obtain stochastic switching between fluorescence ON- and OFF-states, enabling PAINT-based nanoscopic imaging in cells and tissues.

• Dokumententyp: Zeitschriftenartikel
• Fakultät: Physik
• Themengebiete: 500 Naturwissenschaften und Mathematik > 530 Physik
• ISSN: 1359-7345
• Sprache: Englisch