DNA-free directed assembly in single-molecule cut-and-paste

Erlich, Katherine R.; Sedlak, Steffen M.; Jobst, Markus A.; Milles, Lukas F. und Gaub, Hermann E. (2019): DNA-free directed assembly in single-molecule cut-and-paste. In: Nanoscale, Vol. 11, No. 2: pp. 407-411

Abstract

Single-molecule cut-and-paste facilitates bottom-up directed assembly of nanoscale biomolecular networks in defined geometries and enables analysis with spatio-temporal resolution. However, arrangement of diverse molecules of interest requires versatile handling systems. The novel DNA-free, genetically encodable scheme described here utilises an orthogonal handling strategy to promote arrangement of enzymes and enzyme networks.

• Item Type: Journal article
• Faculties: Physics
• Subjects: 500 Science > 530 Physics
• ISSN: 2040-3364
• Language: English