Abstract
This is the last part of an investigation of microdosimetric concepts relevant to numerical calculations. A formula is derived which permits the computation of the dose average lineal energy, $$\bar yD$$ , or the corresponding average of the specific energy without the need to determine the probability distributions,f(y) orf 1(z). A detailed treatment is given for two cases of practical importance. The first case corresponds to spherical sites with diameters of the order of 1 µm and to neutrons up to 15 MeV. The second case corresponds to microscopic sites which are small enough that the change of the stopping power of charged particles traversing the site can be neglected. This investigation was supported by Contract AT(11-1)3243 from the United States Atomic Energy Commission and Public Health Service Research Grants No. CA 12536 and CA 15307 from the National Cancer Institute.
Dokumententyp: | Zeitschriftenartikel |
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Fakultät: | Medizin |
Themengebiete: | 600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin und Gesundheit |
URN: | urn:nbn:de:bvb:19-epub-8310-4 |
ISSN: | 0301-634X |
Dokumenten ID: | 8310 |
Datum der Veröffentlichung auf Open Access LMU: | 11. Dez. 2008, 10:20 |
Letzte Änderungen: | 04. Nov. 2020, 12:50 |
Literaturliste: | 1. Baum, J. W.: Comparison of distance- and energy-restricted linear energy transfer for heavy particles with 0.25 to 1000 MeV/AMU. In: Proceedings of 2nd Symposium on Microdosimetry (Ebert, H. G.Ed.) pp. 653–666. Euratom, 4452 d-f-e (1970) 2. Berger, M. J.: Some new transport calculations of the deposition of energy in biological materials by low-energy electrons. In: Proceedings of 4th Symposium on Microdosimetry (Ebert, H. G.,Ed.) pp. 695–715. Euratom 5122 d-e-f (1974) 3. Caswell, R. S.: Deposition of energy by neutrons in spherical cavities. Radiat. Res.27, 92–107 (1966) 4. Caswell, R. S., Coyne, J. J.: Secondary particle spectra produced by neutron interactions with tissue. In: Proceedings of 1st Symposium on Neutron Dosimetry in Biology and Medicine (Burger, G., Schraube, H., Ebert, H. G.,Eds.), pp. 25–41. Euratom, 4896 d-f-e (1972) 5. Chatterjee, A., Maccabee, H., Tobias, C.: Radial cut-off LET and radial cut-off dose calculations for heavy charged particles in water. Radiat. Res.54, 479–494 (1973) 6. Fain, J., Monnin, M., Montret, M.: Energy density deposited by a heavy ion around its path. In: Proceedings 4th Symposium on Microdosimetry (Ebert, H. G.,Ed.), pp. 169–188. Euratom d-e-f (1974) 7. Glass, W. A., Roesch, W. C.: Measurement of ionization distributions in tissue-equivalent gas. Radiat. Res.49, 477–494 (1972) 8. Gross, W., Rodgers, R. C.: Heavy ion event spectra. In: Proceedings of 3rd Symposium on Microdosimetry (Ebert, H. G.,Ed.), pp. 873–887. Euratom 4810 d-f-e (1972) 9. ICRU: Linear Energy Transfer, Report 16. Washington, D.C.: International Commission of Radiation Units and Measurements 1970 10. ICRU: Radiation Quantities and Units, Report 19. Washington, D.C.: International Commission of Radiation Units and Measurements 1971 11. Katz, R., Kobetich, E. J.: Particle tracks in condensed matter. In: Charged Particle Tracks in Solids and Liquids (Adams, G. E., Bewley, D. K., Boag, J. W.,Eds.), pp. 109– 119. The Institute of Physics and the Physical Society Conference Series No. 8, London (1970) 12. Kellerer, A. M.: Considerations on the random traversal of convex bodies and solutions for general cylinders. Radiat. Res.47, 359–376 (1971) 13. Kellerer, A. M., Bell, W.: Theory of microdosimetry. In: Annual Report on Research Project, USAEC, NYO-2740-7, 73–90 (1970) 14. Kellerer, A. M., Chmelevsky, D.: Concepts of microdosimetry. I. Quantities. Radiat. and Environm. Biophysics12, 61–69 (1975) 15. Kellerer, A. M., Chmelevsky, D.: Concepts of microdosimetry. II. Probability distributions of the microdosimetric variables. Radiat. and Environm. Biophysics12, 205–216 (1975) 16. Kellerer, A. M., Chmelevsky, D.: Criteria for the applicability of LET. Radiat. Res.63, 226–234 (1975) 17. Kellerer, A. M., Chmelevsky, D., Teedla, P.: Numerical derivation of microdosimetric quantities, II. Mean values of the dose distributions. In: Annual Report ERDA No. COO-3243-4, pp. 68–79 (1975) 18. Kellerer, A. M., Rossi, H. H.: Summary of quantities and functions employed in microdosimetry. In: Proceedings 2nd Symposium on Microdosimetry (Ebert, H. G.,Ed.), pp. 843–853. Euratom 4452 d-f-e (1970) 19. Kellerer, A. M., Rossi, H. H.: The theory of dual radiation action. Current Topics in Radiat. Res.8, 85–158 (1972) 20. Kellerer, A. M., Rossi, H. H.: Numerical derivation of microdosimetric quantities, I. Mean values of the frequency distributions. In: Annual Report ERDA No. COO-3243-4. pp. 61–67 (1975) 21. Kendall, M. G., Moran, P. A. P.: Geometrical probability. New York: Hafner 1963 22. Kliauga, P., Dvorak, R., Rossi, H. H., Kellerer, A. M.: Microdosimetric distributions as a function of radial distance from heavy ions. In: Annual Report ERDA No. 3243-4, p. 88–103 (1975) 23. Kliauga, P., Rossi, H. H.: Microdosimetric distributions as a function of radial distance from heavy ion tracks. In: Proceedings 5th Symposium on Microdosimetry, Verbania, 1975 (in press) 24. Paretzke, H. G., Leuthold, G., Burger, G., Jacobi, W.: Approaches to physical track structure calculations. In: Proceedings 4th Symposium on Microdosimetry (Ebert, H. G.,Ed.), pp. 123–140. Euratom, 5122 d-e-f (1974) 25. Paretzke, H. G.: Comparison of track structure calculations with experimental results. In: Proceedings 4th Symposium on Microdosimetry (Ebert, H. G.,Ed.), pp. 141–168. Euratom, 5122 d-e-f (1974) 26. Patau, J. P., Malbert, M., Terrissol, M., Commanay, L.: Études dosimétriques dans des cavités sphériques situées en milieu semi-infini, irradié par des électrons de 2 MeV. In: Proceedings 4th Symposium on Microdosimetry (Ebert, H. G.,Ed.), pp. 755–777. Euratom, 5122 d-e-f (1974) 27. Rossi, H. H.: Energy distribution in the absorption of radiation. Advanc. biol. med. Phys.11, 27–85 (1967) 28. Rossi, H. H.: Microscopic energy distribution in irradiated matter. In: Radiation Dosimetry (Attix, F. H., Roesch, W. C.,Eds.), Vol. 1, pp. 43–92. New York: Academic Press 1968 29. Varma, M. N., Baum, J. W., Kuehner, A. V.: Energy deposition by heavy ions in a ldquotissue equivalentrdquo gas. Radiat. Res.62, 1–11 (1975) |