Abstract
The thiolation of pyridine-2-sulfonamides using magnesium thiolates is reported. The ortho -functionalizations of these sulfonamides using TMPMgCl center dot LiCl (TMP = 2,2,6,6-tetramethylpiperidyl) followed by electrophilic quenching produced a range of 3-functionalized pyridine-2-sulfonamides, which were subsequently converted into the corresponding thioethers. Finally, symmetric or asymmetric diorganodisulfides were employed as electrophiles in a one-pot ortho -functionalization-thiolation procedure, leading to pyridine 2,3-disubstituted dithioethers.
| Dokumententyp: | Zeitschriftenartikel |
|---|---|
| Fakultät: | Chemie und Pharmazie > Department Chemie |
| Themengebiete: | 500 Naturwissenschaften und Mathematik > 540 Chemie |
| ISSN: | 0039-7881 |
| Sprache: | Englisch |
| Dokumenten ID: | 83280 |
| Datum der Veröffentlichung auf Open Access LMU: | 15. Dez. 2021, 15:07 |
| Letzte Änderungen: | 15. Dez. 2021, 15:07 |
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