Iron-Catalyzed Cross-Coupling of Functionalized Benzylmanganese Halides with Alkenyl Iodides, Bromides, and Triflates

Desaintjean, Alexandre; Belrhomari, Sophia; Rousseau, Lidie; Lefevre, Guillaume und Knochel, Paul (2019): Iron-Catalyzed Cross-Coupling of Functionalized Benzylmanganese Halides with Alkenyl Iodides, Bromides, and Triflates. In: Organic Letters, Vol. 21, No. 21: pp. 8684-8688

Abstract

Various substituted benzylic manganese chlorides were prepared by insertion of magnesium turnings in the presence of MnCl2 center dot 2LiCl in THF at -5 degrees C within 2 h. These benzylic manganese reagents underwent smooth cross-couplings with various functionalized alkenyl iodides, bromides, and triflates or iodoacrylates in the presence of 10 mol % FeCl2 at 25 degrees C for 1-12 h. Mechanistic studies showed that benzylic manganese halides produced, in the presence of FeCl2, a very reactive iron ate complex.

• Item Type: Journal article
• Faculties: Chemistry and Pharmacy > Department of Chemistry
• Subjects: 500 Science > 540 Chemistry
• ISSN: 1523-7060
• Language: English