Balkenhohl, Moritz; Jangra, Harish; Lenz, Tobias; Ebeling, Marian; Zipse, Hendrik; Karaghiosoff, Konstantin und Knochel, Paul
(2019):
Lewis Acid Directed Regioselective Metalations of Pyridazine.
In: Angewandte Chemie-International Edition, Vol. 58, No. 27: pp. 9244-9247
Abstract
Mono- or bidentate boron Lewis acids trigger a regioselective magnesiation or zincation of pyridazine in position C3 (ortho product) or C4 meta product). The regioselectivity of the metalation was rationalized with the help of calculated pK(a) values of both pyridazine and pyridazine/Lewis acid complexes.
| Item Type: | Journal article |
|---|---|
| Faculties: | Chemistry and Pharmacy > Department of Chemistry |
| Subjects: | 500 Science > 540 Chemistry |
| ISSN: | 1433-7851 |
| Language: | English |
| Item ID: | 83347 |
| Date Deposited: | 15. Dec 2021 15:07 |
| Last Modified: | 15. Dec 2021 15:07 |
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