Logo Logo
Hilfe
Hilfe
Switch Language to English

Winter, Nils und Trauner, Dirk (2019): Synthesis of acremines A, B and F and studies on the bisacremines. In: Beilstein Journal of Organic Chemistry, Bd. 15: S. 2271-2276

Volltext auf 'Open Access LMU' nicht verfügbar.

Abstract

The acremines are a family of meroterpenoids isolated from fungi of the genus Acremonium. Here, we present the asymmetric total synthesis of acremine F which hinges on a modestly enantioselective dihydroxylation and a subsequent kinetic resolution via a highly selective asymmetric reduction. Chemoselective oxidation of acremine F gave access to acremines A and B. The dimerization of acremine F to bisacremine E was investigated but could not be achieved, shedding light on the formation of the acremine dimers in nature.

Dokument bearbeiten Dokument bearbeiten