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Galldiks, Norbert; Suchorska, Bogdana; Albert, Nathalie L. ORCID logoORCID: https://orcid.org/0000-0003-0953-7624 und Tonn, Jörg C. (2020): Metabolic Imaging of Brain Metastasis. In: Ahluwalia, Manmeet; Metellus, Philippe und Soffietti, Riccardo (Hrsg.): Central Nervous System Metastases. Cham: Springer. S. 159-171

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Abstract

Brain metastases from extracranial cancer are associated with significant morbidity and mortality. Local treatment options are neurosurgical resection and radiotherapy, e.g., radiosurgery or fractionated external beam radiotherapy. Furthermore, systemic treatment options for control of both intracranial and extracranial disease are increasingly gaining importance. Usually, diagnosis, treatment planning, and follow-up is based on contrast-enhanced magnetic resonance imaging (MRI). However, structural imaging modalities have limitations, particularly in terms of the diagnosis of posttherapeutic reactive changes as well as the assessment of treatment response. Metabolic imaging techniques such as positron emission tomography (PET) can characterize specific metabolic and cellular features which may provide clinically relevant information beyond structural MRI.

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