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Queissert, Fabian; Huesch, Tanja; Kretschmer, Alexander; Anding, Ralf; Kirschner-Hermanns, Ruth; Pottek, Tobias; Olianas, Roberto; Friedl, Alexander; Homberg, Roland; Pfitzenmaier, Jesco; Naumann, Carsten M.; Nyarangi-Dix, Joanne; Hofmann, Torben; Rose, Achim; Schweiger, Josef; Huebner, Wilhelm; Loertzer, Hagen; Bauer, Ricarda M.; Haferkamp, Axel; Schrader, Andres J. (2020): High/low-volume center experience predicts outcome of AMS 800 in male stress incontinence: Results of a large middle European multicenter case series. In: Neurourology and Urodynamics, Vol. 39, No. 6: pp. 1856-1861
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Abstract

Aim: To analyze the influence of implantation volume of artificial sphincters (AMS 800) on outcome in a large central European multicenter cohort study. Methods As part of the DOMINO (Debates on Male Incontinence) project, the surgical procedures and outcomes were retrospectively analyzed in a total of 473 patients who received an artificial sphincter (AMS 800) between 2010 and 2012. Clinics that implanted at least 10 AMS 800 per year were defined as high-volume centers. Results Sixteen centers had a mean rate of 9.54 AMS 800/y of which five clinics were identified as high-volume centers. They implanted significantly more double cuffs (55% vs 12.1%;P < .001), used the perineal approach significantly more often (78% vs 67.7%;P = .003) and chose larger mean cuff sizes (4.63 cm vs 4.42 cm;P = .002). With a mean follow-up of 18 months, the revision rate was significantly higher at low-volume centers (38.5% vs 26.7%;P = .037), urethral erosion being the main reason for revision. Social continence (0-1 pads/24 h) was achieved significantly more often in high-volume centers (45.5% vs 24.2%;P = .002). Conclusions: Our study showed significantly better continence results and lower revision rates at high-volume centers, confirming earlier results that are still true in this decade. We, therefore, recommend surgery for male incontinence at qualified centers.