Recollections of the discovery of promiscuous antigen expression in mTECs

Klein, Ludger (2020): Recollections of the discovery of promiscuous antigen expression in mTECs. In: Nature Immunology, Bd. 21, Nr. 11: S. 1303-1305

Abstract

Whether and how thymic tolerance to tissue-restricted antigens (TRA) could be achieved posed a conundrum until Klein and colleagues discovered that medullary thymic epithelial cells were capable of bursts of TRA expression.

• Dokumententyp: Zeitschriftenartikel
• Fakultät: Medizin
• Themengebiete: 600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin und Gesundheit
• ISSN: 1529-2908
• Sprache: Englisch