Das ZEPmax-Programm – effektive, leitliniengerechte multimodale Therapie von Adipositas und Folgeerkrankungen

Bischoff, Gert; Bischoff, Monika; Benend, Veronika; Feiner, Sebastian; Hohenester, Simon und Rust, Christian (2020): Das ZEPmax-Programm – effektive, leitliniengerechte multimodale Therapie von Adipositas und Folgeerkrankungen. In: Aktuelle Ernahrungsmedizin, Bd. 45, Nr. 06: S. 416-423

Abstract

Background: Obesity and related diseases are associated not only with an increased morbidity and mortality, but also with a reduced quality of life. Although a multimodal conservative therapy is recommended by guidelines, suitable programs are not offered nationwide in Germany and the response rates of unstructured interventions are insufficient. Material and Methods The ZEPmax-Program is a conservative, multimodal, one-year therapy program with an initial formula diet for adults with obesity. The patients meet once a week for 3,5 hours at the center. In all 136 patients were included in this evaluation. Besides weight and BMI also the factors of the metabolic syndrome were assessed in an Intention-to-treat analysis. Results: The participants had an average BMI of 43,0 kg/m(2). 11,8% did not complete the one-year program. The patients lost 24,7 kilograms or respectively 19% of the initial weight and 87,5% reached the therapeutic goal of 10% relative weight loss. 72% of the patients with diabetes (n=18) achieved a complete remission with normal HbA1c and without medication. The systolic blood pressure of the patients with hypertension (n=53) dropped by 22mmHg. The cholesterol in patients with hyperlipidemia (n = 66) could be lowered by 23mg/dl and the LDL-Cholesterol by 17mg/dl. Conclusion This survey shows that a sustained weight loss with high response rates can be achieved with a structured, formuladiet-based multimodal obesity treatment program (ZEPmax). Obesity related diseases like diabetes, hypertension and hyperlipidemia could be treated with high remission rates by an effective treatment of obesity. This evaluation demonstrates the significance of a professionally conducted conservative obesity treatment in Germany.

• Dokumententyp: Zeitschriftenartikel
• Fakultät: Medizin
• Themengebiete: 600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin und Gesundheit
• ISSN: 0341-0501
• Sprache: Deutsch