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Schmidt, Martin; Tesche, Christian; Hapfelmeier, Alexander; Finsterer, Sebastian; Valassis, Gregorius; Ebersberger, Ullrich; Schlueter, Mathis; Ziegler, Martin and Kraemer, Björn F. (2020): Significant Radiation Dose Reduction Using a Novel Angiography Platform in Patients Undergoing Cryoballoon Pulmonary Vein Isolation. In: Journal of Thoracic Imaging, Vol. 35, No. 3: pp. 167-172

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Objectives: Cryoballoon pulmonary vein isolation (cPVI) in patients with atrial fibrillation requires fluoroscopic guidance, causing a relevant amount of radiation exposure. Strategies to reduce radiation exposure in electrophysiologic procedures and specifically cPVI are of great importance. The aim of this study was to evaluate a possible reduction of radiation dose using the novel Azurion 7 F12 x-ray system compared with its predecessor Allura FD10. Methods: In February 2017, the Philips Azurion angiography system was introduced, combining the Allura Clarity radiation dose reduction technology with a more powerful generator, improved image resolution, and a large screen display. In 173 patients undergoing cPVI by a single experienced operator in our institution between December 2016 and April 2018, dose area products (cGyxcm(2)) and image quality were compared using Azurion 7 F12 or Allura FD10 angiography system. Results: A significant reduction in total radiation dose expressed as a dose area products of 524 (332;821) cGyxcm(2) on the Allura system compared with 309 (224;432) cGyxcm(2) on the Azurion system was observed (P<0.001). The number of imaging scenes recorded were 14.7 versus 13.9, and mean overall imaging quality scores (grading 4.85 +/- 0.4 with Azurion vs. 4.80 +/- 0.4 with Allura, P=0.38) and scores based on specific quality parameters were similar in both groups. Conclusion: Use of the new Azurion 7 F12 angiography system substantially reduced radiation doses compared with the previous generation reference system, Allura Clarity, without compromising imaging quality in patients undergoing cryoballoon pulmonary vein isolation.

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