Efficacy and safety results of micellar water, cream and serum for rosacea in comparison to a control group

Guertler, Anne; Jontvedt, Nora Marie; Clanner-Engelshofen, Benjamin M.; Cappello, Christian; Sager, Angelika und Reinholz, Markus (2020): Efficacy and safety results of micellar water, cream and serum for rosacea in comparison to a control group. In: Journal of Cosmetic Dermatology, Bd. 19, Nr. 10: S. 2627-2633

Abstract

Background: Rosacea is a common inflammatory skin disorder with centrofacial erythema, flushing, telangiectasia, papules/pustules, and possible ocular or phymatous manifestation. Patients' skin is particularly sensitive to chemical and physical stimuli leading to burning, stinging, dryness, and skin tightness. Objective: Dermatological evaluation of the efficacy and safety of skin care products designed for centrofacial erythema in rosacea patients, in comparison with a control group using objective measurements. Rosacea symptoms (itching, tension, warmth, burning, dryness) and quality of life were examined. Methods Sixty Caucasians with centrofacial erythema were enrolled in an 8-week prospective study, fifty of them exclusively using the study products (micellar water, cream, and serum) with ten participants randomly assigned to a control group. Patients were evaluated at baseline (V0), at 4 weeks (V1), and at 8 weeks (V2). Three-dimensional objective measurements (VECTRA(R)) as well as standardized questionnaires were used. Results: Results were compared with the control group. A significant reduction of 16% in skin redness as indicated by VECTRA(R)analysis was seen in the intervention group comparing V0-V2. Furthermore, rosacea-associated symptoms diminished by 57.1%, while life quality of affected patients within the intervention group improved by 54.5% comparing V0-V2, respectively. Conclusions: A skin care regime suitable for sensitive and redness-prone skin led to an enhanced clinical appearance, to a decrease of associated symptoms in rosacea patients, and to an improved life quality.

• Dokumententyp: Zeitschriftenartikel
• Fakultät: Medizin
• Themengebiete: 600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin und Gesundheit
• ISSN: 1473-2130
• Sprache: Englisch