Drug Resistance Spread in 6 Metropolitan Regions, Germany, 2001-2018

Stecher, Melanie; Chaillon, Antoine; Stephan, Christoph; Knops, Elena; Kohmer, Niko; Lehmann, Clara; Eberle, Josef; Bogner, Johannes; Spinner, Christoph D.; Eis-Huebinger, Anna Maria; Wasmuth, Jan-Christian; Schaefer, Guido; Behrens, Georg; Mehta, Sanjay R.; Vehreschild, Jörg Janne und Hoenigl, Martin (2020): Drug Resistance Spread in 6 Metropolitan Regions, Germany, 2001-2018. In: Emerging Infectious Diseases, Bd. 26, Nr. 10: S. 2439-2443

Abstract

We analyzed 1,397 HIV-1 pol sequences of antiretroviral therapy-naive patients in a total of 7 university hospitals in Bonn, Cologne, Frankfurt, Hamburg, Hannover, and Munich, Germany. Phylogenetic and network analysis elucidated numerous cases of shared drug resistance mutations among genetically linked patients;K103N was the most frequently shared mutation.

• Dokumententyp: Zeitschriftenartikel
• Fakultät: Medizin
• Themengebiete: 600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin und Gesundheit
• ISSN: 1080-6040
• Sprache: Englisch