Angiotensin II Type 1 Receptor Autoantibodies in Primary Aldosteronism

Meyer, Lucie S.; Gong, Siyuan; Reincke, Martin und Williams, Tracy Ann (2020): Angiotensin II Type 1 Receptor Autoantibodies in Primary Aldosteronism. In: Hormone and Metabolic Research, Bd. 52, Nr. 6: S. 379-385

Abstract

Primary aldosteronism (PA) is the most common form of endocrine hypertension. Agonistic autoantibodies against the angiotensin II type 1 receptor (AT(1)R-Abs) have been described in transplantation medicine and women with pre-eclampsia and more recently in patients with PA. Any functional role of AT(1)R-Abs in either of the two main subtypes of PA (aldosterone-producing adenoma or bilateral adrenal hyperplasia) requires clarification. In this review, we discuss the studies performed to date on AT(1)R-Abs in PA.

• Dokumententyp: Zeitschriftenartikel
• Fakultät: Medizin
• Themengebiete: 600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin und Gesundheit
• ISSN: 0018-5043
• Sprache: Englisch