| Yang, Huixia; Kuhn, Christina; Kolben, Thomas; Ma, Zhi; Lin, Peng; Mahner, Sven; Jeschke, Udo; Schoenfeldt, Viktoria von (2020): Early Life Oxidative Stress and Long-Lasting Cardiovascular Effects on Offspring Conceived by Assisted Reproductive Technologies: A Review. In: International Journal of Molecular Sciences, Vol. 21, No. 15, 5175 |
Full text not available from 'Open Access LMU'.
DOI: 10.3390/ijms21155175
Abstract
Assisted reproductive technology (ART) has rapidly developed and is now widely practised worldwide. Both the characteristics of ART (handling gametes/embryos in vitro) and the infertility backgrounds of ART parents (such as infertility diseases and unfavourable lifestyles or diets) could cause increased oxidative stress (OS) that may exert adverse influences on gametogenesis, fertilisation, and foetation, even causing a long-lasting influence on the offspring. For these reasons, the safety of ART needs to be closely examined. In this review, from an ART safety standpoint, the origins of OS are reviewed, and the long-lasting cardiovascular effects and potential mechanisms of OS on the offspring are discussed.
| Item Type: | Journal article |
|---|---|
| Faculties: | Medicine |
| Subjects: | 600 Technology > 610 Medicine and health |
| Language: | English |
| ID Code: | 88108 |
| Deposited On: | 25. Jan 2022 09:26 |
| Last Modified: | 25. Jan 2022 09:26 |
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