Phenotypic heterogeneity of microbial populations under nutrient limitation

Gasperotti, Ana; Brameyer, Sophie; Fabiani, Florian; Jung, Kirsten (2020): Phenotypic heterogeneity of microbial populations under nutrient limitation. In: Current Opinion in Biotechnology, Vol. 62: pp. 160-167

Abstract

Phenotypic heterogeneity is a phenomenon in which genetically identical individuals have different characteristics. This behavior can also be found in bacteria, even if they grow as monospecies in well-mixed environments such as bioreactors. Here it is discussed how phenotypic heterogeneity is generated by internal factors and how it is promoted under nutrient-limited growth conditions. A better understanding of the molecular levels that control phenotypic heterogeneity could improve biotechnological production processes.

• Item Type: Journal article
• Faculties: Biology > Department Biology I
• Subjects: 500 Science > 570 Life sciences; biology
• ISSN: 0958-1669
• Language: English