Abstract
The versatile proteasome inhibitor MG132 is inactivated with a photolabile protection group at its reactive aldehyde function, as described by Esther Zanin et al. in their Research Article (DOI: 10.1002/anie.202008267). Upon blue light irradiation MG132 activity is restored and cancer cells arrest either during metaphase of the cell cycle or die by apoptosis.
Item Type: | Journal article |
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Faculties: | Biology > Department Biology II |
Subjects: | 500 Science > 570 Life sciences; biology |
ISSN: | 1433-7851 |
Language: | English |
Item ID: | 90226 |
Date Deposited: | 25. Jan 2022, 09:34 |
Last Modified: | 25. Jan 2022, 09:34 |