Molecular and classical cytogenetic analyses demonstrate an apomorphic reciprocal chromosomal translocation in Gorilla gorilla

Stanyon, Roscoe; Wienberg, Johannes; Romagno, D.; Bigoni, F.; Jauch, Anna und Cremer, Thomas (1992): Molecular and classical cytogenetic analyses demonstrate an apomorphic reciprocal chromosomal translocation in Gorilla gorilla. In: American Journal of Physical Anthropology, Vol. 88, No. 2: pp. 245-250

Abstract

The existence of an apomorphic reciprocal chromosomal translocation in the gorilla lineage has been asserted or denied by various cytogeneticists. We employed a new molecular cytogenetic strategy (chromosomal in situ suppression hybridization) combined with high-resolution banding, replication sequence analysis, and fluorochrome staining to demonstrate that a reciprocal translocation between ancestral chromosomes homologous to human chromosome 5 and 17 has indeed occurred.

• Item Type: Journal article
• Keywords: In situ hybridization, chromosome banding, phylogeny, primates
• Faculties: Medicine
• Subjects: 600 Technology > 610 Medicine and health
• ISSN: 1096-8644