Machine learning for non‐invasive sensing of hypoglycaemia while driving in people with diabetes

Lehmann, Vera; Zueger, Thomas; Maritsch, Martin ; Kraus, Mathias; Albrecht, Caroline; Bérubé, Caterina; Feuerriegel, Stefan ; Wortmann, Felix; Kowatsch, Tobias; Styger, Naïma; Lagger, Sophie; Laimer, Markus; Fleisch, Elgar and Stettler, Christoph (2023): Machine learning for non‐invasive sensing of hypoglycaemia while driving in people with diabetes. In: Diabetes, Obesity and Metabolism, Vol. 25, No. 6: pp. 1668-1676

Abstract

Aim To develop and evaluate the concept of a non-invasive machine learning (ML) approach for detecting hypoglycaemia based exclusively on combined driving (CAN) and eye tracking (ET) data.

Materials and Methods We first developed and tested our ML approach in pronounced hypoglycaemia, and then we applied it to mild hypoglycaemia to evaluate its early warning potential. For this, we conducted two consecutive, interventional studies in individuals with type 1 diabetes. In study 1 (n = 18), we collected CAN and ET data in a driving simulator during euglycaemia and pronounced hypoglycaemia (blood glucose [BG] 2.0-2.5 mmol L−1). In study 2 (n = 9), we collected CAN and ET data in the same simulator but in euglycaemia and mild hypoglycaemia (BG 3.0-3.5 mmol L−1).

Results Here, we show that our ML approach detects pronounced and mild hypoglycaemia with high accuracy (area under the receiver operating characteristics curve 0.88 ± 0.10 and 0.83 ± 0.11, respectively).

Conclusions Our findings suggest that an ML approach based on CAN and ET data, exclusively, enables detection of hypoglycaemia while driving. This provides a promising concept for alternative and non-invasive detection of hypoglycaemia.

• Item Type: Journal article
• Keywords: Artificial Intelligence, AI, Künstliche Intelligenz, KI
• Faculties: Munich School of Management > Institute of Artificial Intelligence (AI) in Management
• Subjects: 000 Computer science, information and general works > 000 Computer science, knowledge, and systems
• ISSN: 1462-8902
• Language: English