Molecular cloning and sequence analysis of the cDNA encoding the human acrosin-trypsin inhibitor (HUSI-II)

Möritz, Annemarie; Lilja, Hans und Fink, Edwin (January 1991): Molecular cloning and sequence analysis of the cDNA encoding the human acrosin-trypsin inhibitor (HUSI-II). In: FEBS Letters, Vol. 278, No. 1: pp. 127-130

Abstract

A complete cDNA clone encoding the human acrosin-trypsin inhibitor HUSI-II has been isolated from a cDNA library of human testis and completely sequenced. The cDNA of 594 bp contained an open reading frame of 252 base pairs, The deduced amino acid sequence comprised the complete amino acid sequence of HUSI-II[1] and a putative signal peptide. Northern blotting analysis revealed that HUSI-II is synthesized in testis, epididymis and seminal vesicle, but not in the prostate gland.

• Item Type: Journal article
• Keywords: Kazal-type inhibitor,Acrosin-trypsin inhibitor (human seminal plasma),Pancreatic secretory trypsin inhibitor (human)
• Faculties: Medicine
• Subjects: 600 Technology > 610 Medicine and health
• ISSN: 0014-5793